Alexander Fleming was a great Scottish biologist and pharmacologist who made way for antibiotic medicines with his discovery of penicillin from the mould “Penicillium notatum”. Fleming’s discoveries brought new hope to mankind in battling certain diseases and treating bacterial infections. Fleming’s various works are recorded in his articles on bacteriology, immunology, and chemotherapy. He won Nobel Prize in Physiology or Medicine in 1945 for his outstanding and breakthrough discovery. Such is the impact of the great man that his name had even featured in the list of 100 Most Important People of the 20th Century as recently as in 1999. Present day penicillin upgrades carried put by the medicine world stand on one man’s quest and that is none other than Fleming. By discovering synthetic penicillin Fleming paved the way for preventing and fighting serious illnesses like syphilis, gangrene and tuberculosis which were never imagined of being treated before Fleming’s discoveries.

CHILDHOOD & EARLY LIFE

>> Alexander Fleming was born in Lochfield farm, Avrshire, Scotland, UK on 6th August 1881. He was born to farmer parents Hugh Fleming and Grace Stirling Morton (second wife of Hugh Fleming). He lost his father due to ill health at a tender age of seven only.

>> Fleming studied at Loudoun Moor School and Darvel School and moved to London at the age of thirteen to attend the Royal Polytechnic institution after attaining two scholarships for Kilmarnock Academy.

>> Following his elder brother Tom’s footsteps he also joined St. Mary’s Hospital Medical School (Paddington) in 1903 to study medicine which he completed with an MBBS degree in 1906.

CAREER

>> Alexander Fleming joined the Research department at St Mary’s and worked as an assistant bacteriologist to Sir Almroth Wright who was a master in vaccine therapy and immunology.

>> In1908 Fleming joined St Mary’s as a lecturer after being awarded a gold medal in bacteriology, and served there till 1914.

>> Fleming practiced as a venereologist between 1909 and 1914. He became the first doctor to administer a drug against syphilis called arsphenamine (Salvarsan).

>> In 1928 he became a professor of bacteriology at the University of London.

>> He was a part of the Royal Army Medical Corps as a captain during the World War I and served in the war field hospitals in France where he studied the effect of antiseptics on the wounds.

>> He returned to St. Mary’s as assistant director of the inoculation department and later became the principal of the same in 1946 which was later renamed as Wright-Fleming Institute.

>> In 1951, he joined the University Of Edinburg as rector for three years.

MAJOR WORKS

>> Antiseptics do more harm than good: While serving the field hospitals during the World War I in 1914 he reached the conclusion that antiseptics such as carbolic acid, boric acid and hydrogen peroxide (used to treat wounds) do more harm than cure. He found that they only cured surface wounds and failed to heal deeper. Along with Almroth Wright, he suggested an alternative of saline water for treatment.

PERSONAL LIFE & LEGACY

>> On 24 December 1915, Alexander Fleming married Sarah Marion McElroy of Ireland, a trained nurse. Their only son Robert, born in 1924, followed his father to become a medical practitioner.

>> Fleming was knighted as Knight Bachelor by King George VI to become Sir Alexander Fleming in 1944.

>> Post Sarah’s death in 1949, Fleming remarried a colleague at St. Mary’s, Dr.Amalia Koutsouri-Vourekas, on 9 April 1953 who died in 1986.

>> Fleming succumbed to a heart attack at the age of 73 on 11 March 1955 and was cremated at St. Paul’s Catheral.

>> Fleming was always modest in accepting his role in the discovery of Penicillin and described his popularity as ‘Fleming Myth”. Nonetheless, he always praised Florey and Chain but still turned out to become the hero of modern healthcare.

>> Sir Henry Harris’ remark says it all: “Without Fleming, no Chain; without Chain, no Florey; without Florey, no Heatley; without Heatley, no penicillin”.

>> On his tour to America, this great scientist and Nobel Prize winner was offered a gift of $100,000 as a token of respect which he did not accept rather donated to the laboratories at St. Mary’s Hospital Medical School.